Questions and Answers | Q&As
Canaloplasty and Recovery
Is the Canaloplasty Procedure a Mere “Marketing Concept”?
QUESTION:
Hello David;
Sorry it has taken a while to get back to you. I did receive my records but upon referral of my PCP, I wanted to see another ophthalmologist to get a second opinion regarding whether or not I needed a trabeculectomy. Mainly this was because of my insurance / financial situation. The other Dr told me that based on his examination I fell into the moderate category of severity of glaucoma. He felt that the trabeculectomy would be a better solution since 90% of my optic nerve has been damaged and my remaining 10% no longer consists of that redundant tissue. If I were in the mild category then a canaloplasty would seem to be a better choice, but my condition is one of exigency he implied.
I know that we have discussed the attitudes of ophthalmologists who won’t perform canaloplasties because of skill and they feel that it is a fad. In fact, he had mentioned that such a procedure is a “marketing concept” and also it takes away a lot of “real estate” of the eye (whatever that means) if further procedures were needed to be done. I had mentioned to him the post op complications associated with trabs, and especially that fact that I am African American, from which such a surgery has the least effectiveness; but his response was the likelihood of that happening to me is not that great and the surgery failing is decreased if I take the proper steps in my post op care. Unlike the other doctor, he spent a great deal of time with me and was willing to try a different combination of medications / minimally invasive procedures to lower my pressure despite his feelings that the trab surgery would be in my best interest.
The most frustrating thing of all this is not so much the disease or the surgeries, but the fact that in the medical community there is a wide gap between those who espouse a certain procedure over the other. You have the canaloplasty surgeons on one side of the fence and the trabeculectomy surgeons on the other with the patients caught in the middle. There seems to be no collaboration on procedures that give us patients a “good feeling” about which direction to take. This has been my experience. He, like other doctors state that the trabeculectomy is the “gold standard” and eliminates all doubt of pressures going back up again in contrast to the other surgeries. He also stated that a canaloplasty was NOT a minimally invasive surgery. So with all the other options on the table, like the shunts, trabectome etc., which he stated are possible, it seemed as if they, along with canaloplasty would simply prolong the inevitable and I would be subject to a trabeculectomy anyway, so why not just cut to the chase? That’s what I got from him.
Anyway, I wanted to keep you in the loop. Please feel free to add your thoughts.
Best
******
ANSWER:
Dear ******,
I also find it sad that most eye surgeons have taken a position on canaloplasty without making the effort to first become adept at it. Then again, it is a difficult surgery to perform so not everyone is capable of mastering it. Perhaps that is what lies behind much of the debate as no surgeon likes to face the idea that there are some surgeries that they might not be able to master.
One of the greatest living glaucoma surgeons, Dr. Robert Stegmann, developed viscocanalostomy as well as canalopalsty and just published a paper showing great 12-15 year results with the less effective viscocanalostomy:
Canaloplasty can on average achieve an IOP 2mmHg lower than viscocanalostomy:
If canaloplasty is a “marketing concept” then it’s failed to succeed in converting surgeons to do it. Dr. Stegmann is a smarter and better surgeon than I. He created canaloplasty to meet a desperate need of treating glaucoma “in the bush” (his words). To whom was he marketing? His patients had no money. Alternatively, if canaloplasty is a fad, it’s a long-term one and will likely be replaced only by better canal-based surgical techniques.
Now, to address some of the other issues mentioned:
“it [canaloplasty] takes away a lot of “real estate” of the eye (whatever that means) if further procedures were needed to be done.”
This is a common, but unsupported, concern among surgeons who do not perform canaloplasty. This issue has been addressed in the literature. Trabeculectomy success was the same whether or not canaloplasty was performed prior to trabeculectomy:
and
“I had mentioned to him the post op complications associated with trabs, and especially that fact that I am African American, from which such a surgery has the least effectiveness; but his response was the likelihood of that happening to me is not that great and the surgery failing is decreased if I take the proper steps in my post op care.”
Interesting response. Perhaps he has discovered the “secret sauce” of trabeculectomy that other skilled and respected glaucoma surgeons have been searching for. Many glaucoma surgeons, however, will admit among themselves that what they hate most about trabeculectomies is that the surgery can go perfectly yet the final outcome cannot be predicted for any individual patient.
“He, like other doctors state that the trabeculectomy is the “gold standard” and eliminates all doubt of pressures going back up again in contrast to the other surgeries.”
Trabeculectomy is the “gold standard” for the reasons I outline here:
Yes, it is the most likely procedure to achieve a low IOP with or without drops. And, it may very well be the best option for you. However, there is a definite risk/reward relationship. You can’t get the single digit IOPs off drops without taking a significant risk. Not everyone, however, needs IOPs that low. Do you?
“So with all the other options on the table, like the shunts, trabectome etc., which he stated are possible, it seemed as if they, along with canaloplasty would simply prolong the inevitable and I would be subject to a trabeculectomy anyway, so why not just cut to the chase?”
Why? Because no glaucoma surgery can be expected to last a lifetime. Do you plan on living for another decade or two or three or…? Then you had better plan on having multiple surgeries for your glaucoma. Might your surgery (canaloplasty or trabeculectomy or something else) last for your lifetime? Sure, it happens. But it’s not to be expected.
Failure rates for trabeculectomy average 10-15% per year with 50% having failed by five years after surgery. These are the rates of published surgeons (probably the best of class). Some have estimated that rates of failure in the community may be even higher.
Canaloplasty is likely to fail at the same rate. So why chose canaloplasty first? Because it’s the safer option and if it doesn’t work (or eventually fails) you can still go on to either a trabeculectomy or glaucoma drainage device (tube).
The question I’d ask is “Why close a door on a safer procedure if you don’t have to?”
Not having examined you in person I don’t know whether you are even a good candidate for canaloplasty. If you do go ahead with trabeculectomy (which, again, for all I know may be the most appropriate option for you) then having trabeculectomy performed with an Ex-PRESS mini-shunt will at least make it easier to perform canaloplasty down the line if (when?) the trabeculectomy fails. Yes, canaloplasty can be performed after trabeculectomy but it’s exponentially more challenging (for a surgery that’s challenging to begin with). At least with a properly placed Ex-PRESS shunt the canal is left intact making canaloplasty only moderately more challenging to do.
A significant limitation of basing an individual decision on probabilities is that you’re not a population, you’re an individual. Ultimately you will chose a surgery and it will either adequately lower your IOP or it won’t. If it doesn’t you move on to the next treatment option. It just makes more sense to me (and I’m the first to admit that not all surgeons agree with this) to start with the lower-risk options and scale up to higher risk only when the lower-risk options fail.
I don’t know whether this was of help to you or not. My hope is that whatever surgery you choose will succeed for many years and do so with no complications. I am also hopeful that once you make your choice you will enjoy peace of mind that it was the “right” choice for you whether it succeeds or not.
Glaucoma surgery is a bit like the “Let’s Make a Deal!” show. You simply won’t know whether you chose correctly until the curtain is lifted (you’ve healed from surgery). There’s no point in berating oneself if the chosen surgery doesn’t work as expected because there are no guarantees.
Worth emphasizing is that no currently available surgery or surgeon is capable of eliminating “all doubt of pressures going back up again in contrast to the other surgeries” even if you “take the proper steps in [your] post op care”.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Oct 15, 2014
Canaloplasty Evaluation and Operation at the Same Day?
QUESTION:
Is it possible to have canaloplasty evaluation and operation at the same day?
ANSWER:
Yes. So long as Ana has all of the information required by the hospital it could be done. However, the in-office examination requires dilation. Unless we are also considering cataract surgery I would prefer the eye to be undilated at the time of cataract surgery. Additionally, the anesthesiologist will prefer that you’ve had at least 24 hours in the USA before undergoing surgery. My preferred approach would be to schedule surgery at least one day after the initial evaluation.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Thu, Jan 15, 2015 at 1:53 AM
What Is an Average Surgery Time for a Canaloplasty?
ANSWER:
Most surgeons can complete Canaloplasty in 45 minutes. I’m slow (and a bit obsessive-compulsive) so I may take over an hour if needed. It’s my belief (shared by the “father” of Canaloplasty, Robert Stegmann) that the incision needs to be water tight in order to force aqueous fluid through the natural drainage system that has just been reopened. Suturing takes time. Time is not something most busy eye surgeons have a lot of.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Sun, Feb 8, 2015 at 3:00 PM
What Is Vision Going to Be Like Right After Canaloplasty Surgery?
QUESTION:
Dr. Richardson, I think I am going to have to have a canaloplasty on my right eye soon. I have already lost all vision in my left eye due to several cornea transplants that were rejected. I am very nervous about this canaloplasty surgery and would like to know what my vision is going to be like right after surgery and in the future. My name is D****** Smith. My email is: ******.
P.S. I live alone and need some vision after the surgery. Please let me know what I should expect.
D****** Smith via Facebook
ANSWER:
Dear ******,
It’s quite understandable to be nervous about surgery on your only functioning eye. Fortunately, canaloplasty is one of the safer incisional glaucoma surgeries. Nonetheless, vision may be blurred for awhile after any glaucoma surgery. With canaloplasty this is often due to reflux of blood cells from the drainage system through the opened canal into the front of the eye. It can take days to weeks for this blood to flow back out the way it came.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: September 29, 2014
I Had LASIK and Iridotomy on Both Eyes. Is Canaloplasty Suitable for Me?
QUESTION:
Dear Ana, thank you for your email. My name is ******. I’m from Indonesia. I’m 40 year old. I found Dr. Richardson website just one day before my trabeculectomy operation. I have canceled the operation and want to find out whether canaloplasty suitable for me.
I have my LASIK in both eyes in January 2010. Before have LASIK my eyes are -5 ( right eye ) and -7 (left eye). The doctor saw my high IOP in both eyes and retinal tears in my right eye. The IOP was at high twenties. After have glaoplus (local name for xalacom), my IOP was stable at 10 – 12. And after retinal laser, my retinal tears problem in the right eye is solved.
Several months after LASIK, my IOP started to elevated again to high twenties. My Doctor who is glaucoma specialist gave me xalacom 1 drop per day in both eye, and my IOP stable at 9 – 11. It lasted for 1 year, when my doctor told me that my high IOP controllable and he will reduce the dose. And suddenly my doctor ask me to stop using xalacom and change to alphagan 3 times drop a day. After using alphagan, I feel pain in my eyes and my IOP rose to high twenties. My Doctor gave me alphagan and azopt, both 3 times a day, no improvement. My Doctor gave me alphagan, azopt and xalacom, still no improvement at all. Quite strange, because previously xalacom worked well to my eyes. My docter gave me alphagan, azopt and duotrav, and it worsening. At that time my IOP rose to high thirties to low forties. After that my doctor recomend laser therapy for my eyes, but I refused.
I switch to other glaucoma specialist, the same cycle is happened again. I started with timolol, glaoplus (local name for xalacom), alphagan, azopt, and at the end my second doctor recommend me for trabeculectomy. I refused. My IOP was still at high thirties and low fourties.
Without advice from doctor, I tried phylocarpine 1%. I worked well, especially for my right eye. The IOP for the right eye could drop to 15. But it seem not affected my left eye. My left eye IOP was still high twenties to low thirties. I can only use phylocarpine at night before sleep. If I use at the other time the result is not that good.
Six month ago I diagnosed hyperthiroid, and still in medication right now. Quite interesting, during early period of hyperthiroid, my eyes improved very very well, even without eye drop. But after got hyperthiroid medicine, my eyes condition back to pre hyperthiroid condition.
I switch to the third glaucoma specialist, and she recommend me iridotomy. Before take the iridotomy I use brimodine (similar to alphagan) 2 times a day and glaucon (local brand for diamox) three time a day. At the iridotomy day, my IOP was quite good, 12 for right eye and 15 for the left eye.
After iridotomy, the IOP rose to mid thirties and low forties. The glaucoma specialist recommend me for trabeculectomy. I try using pylocarpine (which previously succes to bring down my IOP to fifteen), but this time was unsuccessful. My IOP is still high thirties to low forties. I am tired, hopeless and agree to have trabeculectomy.
As I said before, I found Dr. Richardson website, and wondering if it suitable for me. I quite rational, the broken nerve cannot be repaired and I do not expect my vision back to normal. I just want to maintain my current optical nerves at lowest risk possible, which I expect from canaloplasty.
You can find my humprey test as attached.
I also cc my email to my sister. My sister already has US visa, but I still don’t have it and try to get it.
While waiting for my US visa, do you have slot for canaloplasty, let say in January 2015?
Btw, my phone number is ******. But because of my english is not that fluent, I prefer using email, because I can think before talk to you.
Thank you
ANSWER:
Hello ******,
Ana forwarded your email to me. I would be happy to evaluate you and (if you are a candidate) we could schedule canaloplasty for January 2015. If you think this is something you would like to pursue please let Ana know so that she can block out some time for your possible surgery.
Without examining your eyes I cannot determine whether you are, indeed, a candidate for canaloplasty. If your angles are open then canaloplasty can be expected to achieve adequate IOP lowering about 85% of the time[1] .
I am concerned, however, that another doctor recommended peripheral iridotomy (PI). This is generally only recommended with narrow angles or pigment dispersion syndrome. If your angles are narrow then canaloplasty alone would not be indicated (though it might be reasonable at the time of cataract surgery). If the reason for laser PI was pigment dispersion then canaloplasty could be a reasonable surgical treatment option.
Hoping this was helpful.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
[1] Lewis RA, von Wolff K, Tetz M, et al. Canaloplasty: Three-year results of circumferential viscodilation and tensioning of Schlemm canal using a microcatheter to treat open-angle glaucoma. J Cataract Refract Surg. 2011;37(4):682-90.
Bull H, von Wolff K, Korber N, Tetz M. Three-year canaloplasty outcomes for the treatment of open-angle glaucoma: European study results. Graefes Arch Clin Exp Ophthalmol. 2011;249(10):1537-45.
Brusini P. Canaloplasty in open-angle glaucoma surgery: a four-year follow-up. ScientificWorldJournal. 2014;2014:469609.
Date: Friday, December 26, 2014 10:47 PM
Can One Redo the Canaloplasty Surgery Again on the Same Eye?
QUESTION:
Hope I am not inconveniencing you in anyway by sending this email directly to you. I would like to know if you can help me with my glaucoma if I come to your clinic in California. I live in Missouri. It may take a while as I am retired and need to get the finance together before coming to see you.
Here is the problem I am facing. I have had canaloplasty surgery on ***. The surgeon did not place stents in the drainage canal as you and others do. He place the sutures.
On July 12th during the follow-up with the doctor, my IOP was at 3 and the surgeon said everything seems to be good and he can see the fluid draining through the drainage system of the eye. On *** during the 7th day check up my IOP was at 6.
I came home after this and went back to the surgeon on *** for the one month check up. At this time my IOP spiked and was at 22. Now, the surgeon said I may have blockage on the internal draining system and wants to Trab surgery. I am really worried and very hesitant to do trab surgery just one moth after Canaloplasty.
It is hard for me to believe the drainage system in my eye is clogged if my IOP is 3 and 6, one week after surgery. This shows the drainage system is working and now is at 22, one month after surgery. This tells me may be there is a blockage in the Schlemm’s Canal.
I would like to get your opinion on this and would like to know if you can help? Or one month is too early to predict the IOP pressure fluctuation after the canaloplasty surgery? Can one redo the canaloplasty surgery again on the same eye?
Thank you in advance for your advise and hope you can help me as I do not want to do the trab surgery.
R**** via Email
ANSWER:
Hello R****,
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
I’ve had Canaloplasty on both eyes but it failed. Why?
October 3, 2016
QUESTION:
I had canaloplasty performed in both eyes July of this year. My surgeon said it didn’t work because my drainage system passed the Canal of Schlems was completely clogged up. My eye pressures have stayed higher, Have you ever heard of this? Thank You
via Email
ANSWER:
I am sorry to hear that your intraocular pressures have not been well-controlled after canaloplasty. It is incredibly frustrating when glaucoma surgery does not achieve the desired result. Many canaloplasty surgeons (myself included) believe that when canaloplasty fails it is due to blockage of the distal collector channel system. Unfortunately, there is no reliable in-office method of assessing the functioning of the collector channels beyond Schlemm’s canal.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Is it possible to have canaloplasty after cataract operation?
February 7, 2017
QUESTION:
I have glaucoma and also need to have cataract surgery and I understand that these two surgeries are now combined for better effect. I am in Australia but I am looking at coming on a visit to USA to have a consultation with Dr. Richardson to see if I am good candidate for canaloplasty. Canaloplasty is not offered in Australia. I have attached my eye doctor’s notes for you to access.
- My glaucoma doctor is happy to take care of me following the canaloplasty surgery here in Australia.
- Is it possible to have canaloplasty after cataract operation? Is the best outcome if both (cataract & canaloplasty) are done at the same time.
- How many canaloplasty surgeries has Dr. Richardson done and how any of them does he do for a year or a month.
- Have you achieved 10-14 pressure with any of his patients with canaloplasty and cataract surgery. How realistic is it for me expect this pressure drop in this range. I am OK with achieving this even with drops if I can stay off having trabeculectomy.
- How long do I have to stay after the canaloplasty operation before I return to Australia.
Can you let me know how I can progress to getting consultation appointment and possible surgery for canaloplasty.
Thanks very much.
via Email
ANSWER:
I’ve had the opportunity to review the letter and test printouts you attached (thank you). From my limited review it does appear that you would be a candidate for canaloplasty. I will address each of your questions below:
1) Is it possible to have canaloplasty after cataract operation? Is the best outcome if both (cataract & canaloplasty) are done at the same time?
It is possible to have canaloplasty after cataract surgery so long as the cataract surgeon has NOT placed an iStent or other “intracanalicular stent” as was suggested in Dr. Okera’s letter. Placement of an iStent or other “intracanalicular stent” is one of the few surgeries after which canaloplasty cannot be done. It would be OK, however, to have endocyclophotocoagulation (ECP) done at the time of cataract surgery if that is available to your local surgeon.
2) How many canaloplasty surgeries has Dr. Richardson done and how any of them does he do for a year or a month?
I have performed over 200 canaloplasty surgeries (possibly 300+ but I stopped counting after 200) and for a while was one of a small group of canaloplasty surgeon instructors. As I no longer participate in insurance or Medicare I am no longer a “high volume” surgeon (which is as I and my patients prefer it). However, I still regularly schedule canaloplasty 1-3 times each month.
3) Have you achieved 10-14 pressure with any of his patients with canaloplasty and cataract surgery? How realistic is it for me expect this pressure drop in this range? I am OK with achieving this even with drops if I can stay off having trabeculectomy.
Yes, that is realistic with anticipated drop use after surgery.
4) How long do I have to stay after the canaloplasty operation before I return to Australia?
I would prefer at least one month though if you heal quickly it might be possible to go back earlier.
Can you let me know how I can progress to getting consultation appointment and possible surgery for canaloplasty.
I have copied my nurse, Ana, on this email so that you may schedule a consultation, anticipated surgery, and travel.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
What moistening eye drops do you recommend after AB Interno Canaloplasty?
June 22, 2017
QUESTION:
I have had AB Interno Canaloplasty with Goniotomy last Tuesday. Wednesday, when my pressure was checked, it was 35. My Dr immediately number my eye and explained he cut through my mesh because it got clogged from all the different eye drops. My question, what moistening eye drops do you recommend after this procedure. I also had a cataract removed. At the same time, I had a severe headache for 48 hours after this post op procedure and my pupil is slightly dilated, so I don’t want this to be repeated if using the right moistening drops will help. I use refresh optive. Thank you for your time.
via Email
ANSWER:
I am sorry to hear about your early experience with Ab-Interno Canaloplasty (ABiC). The good news is that most early IOP elevations are transient so will often resolve with time. With regard to dry eye therapy, I generally make therapy recommendations based upon the appearance of the tear film at the slit lamp. Given the fact that I’ve not examined your eyes, I’m afraid I cannot offer a specific recommendation tailored to your ocular surface condition.
Sorry I could not be of greater assistance.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
The Good, Bad, and Ugly With Ab-interno Canaloplasty (ABiC™)
November 5, 2018
QUESTION [from an eye surgeon]:
I’m planning to start trying iTrack, after using iStents for 4 years now. Any advice on the good, bad, and ugly with this type of canaloplasty?
Thanks,
via Email
ANSWER:
When it comes to canaloplasty, I’m a bit of an “old dog” in that I still prefer the Ab-Externo technique as I primarily treat moderate to severe glaucoma in my practice and need all four IOP lowering elements of the surgery: dilation and stenting of the canal, and trans-scleral percolation into both the suprachoroidal space and subconjunctival space. That being said, I’ve been using Ab-Interno canaloplasty with the Ellex iTrack microcatheter more frequently as I’ve been impressed with how easy and effective it has been in my patients with mild to moderate glaucoma. I’ve even recently used it in patients with advanced glaucoma (who for other reasons were not candidates for ab-externo procedures).
My experience is that when combined with cataract surgery it’s about as effective as the other available (and previously available) MIGS options: an average of 1-3 mmHg IOP reduction beyond what cataract surgery alone would be expected to do. Where ABiC seems to shine is in the phakic or pseudophakic patients. It’s not tied to cataract surgery as with other MIGS procedures as the code was approved prior to MIGS existing.
As an important aside, it’s worth noting that the code for ABiC (66174, canaloplasty without stent) can be used with all forms of “primary or chronic open angle glaucoma” (mild, moderate, or severe) and is payable regardless of phakic status. For those who are already comfortable with the iStent but would like to offer their pseudophakic patients a MIGS option (for which they won’t be on the financial hook). ABiC is a great option. Medicare and most commercial insurances (payment from Blue Cross varies by state) will pay for the procedure. Indeed, this is the route I generally recommend for those considering ABiC. We all have patients who have already had cataract surgery but would likely benefit from MIGS. Ab-Interno canaloplasty is a great option for these patients.
Given that my experience is anecdotal, I’ve copied the results section from a recently published study by Mark Gallardo, Richard Supnet, and Ike Ahmed:
“The study included 75 eyes of 68 patients (mean age: 73.7±9.9 years) with a mean base-line IOP of 20.4±4.7 mmHg on 2.8±0.9 medications, which reduced to 13.3±1.9 mmHg (n=73) on 1.1±1.1 medications at 12 months postoperative (both P,0.0001). At 12 months, 40% of eyes were medication free. In the ABiC/phacoemulsification subgroup (n=34 eyes), the mean IOP and medication use decreased from 19.4±3.7 mmHg on 2.6±1.0 medications preoperatively to 13.0±1.8 mmHg on 0.8±0.2 medications at 12 months (both P,0.001). In the stand-alone ABiC subgroup (n=41), the mean IOP and medication use decreased from 21.2±5.3 mmHg on 3.0±0.7 medications preoperatively to 13.7±1.9 mmHg on 1.3±1.1 medications at 12 months (P=0.001 and ,0.001, respectively). No serious adverse events were recorded.”
No doubt there will be surgeons (many of whose opinion I greatly respect) who currently see no benefit to ABiC over GATT. With regard to the use of GATT, however, I strongly disagree. When the Ab-Externo form of trabeculotomy was initially studied decades ago it was given up because although it had an impressive initial effect, it eventually failed in adults. In peds the trabecular meshwork has a congenital obstruction so it works in that population. However, in adults the trabecular leaflets tend to scar down over time potentially worsening the outflow issue beyond pre-trabeculotomy. Thus, innovations such as the Trabectome and Kahook Dual Blade (KDB) were developed, the purpose of which is to remove the leaflets left by GATT that can obstruct outflow over time.
Even Trabectome and KDB, however, suffer from destruction of the trabecular meshwork. There is growing evidence that the trabecular meshwork is far from just a drainage grate and should be preserved if possible. Indeed, there is an impressive amount of work from Murray Johnstone demonstrating dynamic pulsatile flow (TM as pump) with direct connections via cylindrical attachments to collector channel flaps that act to open and close access to the collector channel system. Removal of the TM could potentially result in the flaps obstructing the collector channel openings (which may be one reason other than scarring of the trabecular leaflets that trabeculotomy eventually seems to fail in adults). Additionally, the elegant work of Darryl R. Overby has demonstrated a complex system of mechanosensory regulation of outflow that is dependent on the trabecular meshwork. Finally, there are multiple new pharmaceutical agents (one already available: Rhopressa) that would be unlikely to have any beneficial effect if the trabecular meshwork has been destroyed. Why eliminate an entire class (or future classes) of TM-dependent treatment options unless there are no other reasonable options?
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Is Canaloplasty for All Types of Glaucoma? Can a Patient Stop the Use of Drops After the Surgery?
ANSWER:
- Canaloplasty is an option for those with open angle glaucoma (the most common type).
- Most people who have canaloplasty are able to stop some (or even all) of their drops. Most people with glaucoma, however, are able to achieve adequate control through life with only drops (no surgery).
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Jul 8, 2013
Will I Be Able to Stop Using Glaucoma Drops After Canaloplasty?
ANSWER:
If you’ve been using glaucoma drops for many years, it’s possible that your surgeon may not achieve full catheterization during canaloplasty. That’s because using drops can have some long term effects on the natural drainage system. That being said, even if full catheterization cannot be achieved, generally pressure reduction can still be achieved by incomplete catheterization and dilation of the canal. This effect, long term of using drops, has more surgeons considering offering canaloplasty earlier before the long term damage has been done to the natural drainage canal. You may want to ask your surgeon whether or not you will be a candidate for canaloplasty earlier on in your glaucoma treatment.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Aug 29, 2013
Will My Vision Change After Canaloplasty?
ANSWER:
It’s important to recognize that the purpose of any glaucoma surgery including canaloplasty, is to prevent further loss of vision, not to improve vision. It’s also important to recognize that after any glaucoma surgery including canaloplasty, the vision immediately after surgery will likely be worse than it was before surgery. In the case of canaloplasty, this is generally because there’s some bleeding inside the eye after surgery. As awful as these sounds, this is actually a good thing. Because bleeding in the eye indicates that the natural drainage canal has been opened, and is connected to the venous collector system. Once that blood goes away which generally is within about one or two weeks, the vision should improve. Another thing that can limit vision after surgery, usually temporarily, is what we call induced astigmatism, which just requires a new pair of glasses to bring your vision back up to what it was before. The interesting and exciting thing about canaloplasty though, is that once you’ve gotten rid of some, or all of your drops, because your pressure’s lower after surgery, your tear film may improve. And if your tear film improves from lack of using all of those drops, then it may be possible for your vision to be a little clear. That’s one of the more exciting thing about canaloplasty as compared to some of the more traditional surgeries which generally do not result in an improve tear film.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Aug 29, 2013
How Long Will My IOP Stay Controlled with Canaloplasty?
ANSWER:
Canaloplasty has been approved by the FDA since 2008. So as of 2012, we have three-year published results, which indicate that the pressure lowering effect of canaloplasty is stable over those three years. Now, three years may not sound like very long, but the older style of surgery, viscocanalostomy, on which canaloplasty is an improvement, has results seven years out. And the seven-year results look very good for that surgery. Since canaloplasty adds to viscocanaloplasty by restoring the natural drainage duct and keeping it open with a stent, we can only imagine that the long term results of canaloplasty are going to be even more impressive.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Aug 29, 2013
Can I Continue to Wear Soft Contact Lenses After Canaloplasty?
ANSWER:
One of the unfortunate things about traditional glaucoma surgeries such as trabeculectomy and tubes or shunts, is that, if you’re a soft contact wearer now, after surgery you may not able to wear soft contact lenses. It is possible for some people to wear hard or rigid gas permeable contact lenses after traditional surgery, but because of the bleb soft lenses are generally not a good idea. One of the benefits of canaloplasty is that in general, if you’re a soft contact lenses wearer before surgery, once the eyes healed from surgery, you should be able to be refit for a new pair of contact lenses after the eye is healed.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Aug 29, 2013
How Will I Limit My Activities After Canaloplasty?
ANSWER:
Immediately after any glaucoma surgery including canaloplasty, you’re going to want to be careful with any kind of activity that requires good stereo vision. Since the vision in the eye that you’ve had surgery may be blurred, it’s important to avoid activities such as driving or working with heavy machinery, until your vision is clear again. Also, until the incision has healed it’s going to be important to avoid any kind of activities that involved submerging the head under water such as swimming or diving or getting the eye dirty such as being out in the dirt gardening. It is however, okay after surgery for you to wash your face, take a shower, wash your hair, go to the hairdresser, things like that.
Date: Aug 29, 2013
How Many Days Does a Patient Have to Wait to Regain Vision After a Canaloplasty Surgery?
ANSWER:
Vision can be blurred for weeks after any glaucoma surgery (canaloplasty included). A common cause of blurred vision after canaloplasty is a hyphema (blood in the eye). This is to be expected and should resolve within weeks. If a hyphema is not the cause of poor vision then there could be a more serious issue. A surgeon should be able to explain the likely cause of poor vision and whether there is reason to be concerned. Fortunately, it is rare for someone to lose significant vision from canaloplasty.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: Jun 17, 2013
Can Canaloplasty Be Always Performed without MMC?
QUESTION:
I have wondering whether canaloplasty can always be performed without MMC? (The uncertain risks long-term are a concern with MMC and therefore any procedure requiring its use, even in small amounts, is out of the question for me ).
******
ANSWER:
Dear ******,
In the hundreds of canaloplasty surgeries I’ve performed, I’ve not once felt the need to use Mitomycin-C (MMC). Frankly, I do not believe MMC has any
useful role in canaloplasty.
Warm regards,
David Richardson, MD
Patient-Focused Ophthalmologist
San Marino Eye
2020 Huntington Drive
San Marino, CA 91108
626.289.7856
Patient-Focused Websites:
New-Glaucoma-Treatments.com
About-Eyes.com
Date: June 20, 2014
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